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JWH-018 use is instantly detected in urine applying "spice" screening immunoassays from various suppliers focused on both the parent drug and its omega-hydroxy and carboxyl metabolites.[25] JWH-018 will not be detected by more mature strategies employed for detecting THC and also other cannabis terpenoids. Determination from the parent drug in serum or its metabolites in urine has been completed by GC-MS or LC-MS.

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